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The anticoagulant Plavix, Sanofi's flagship drug, loses its patent on Thursday the United States. Although long-expected, this is a difficult stage for the championship tricolor pharmacy. The arrival of generics is usually depressing sales of an original drug by 80% within months. However, in 2011, sales of Plavix in the United States accounted for 4.8 billion euros. In accounting terms, the decline in sales will have no impact on the accounts of the champion tricolor because the marketing of its flagship product is provided by the U.S. laboratory BMS.

The benefit of Sanofi will, however, heavily impacted. In 2012, the group's net profit will suffer an impact of 1.4 billion euros, due to the loss of U.S. patents on two products, Aprovel / Avapro in March and especially Plavix May 17, announced Chris Viehbacher, CEO of Sanofi in February.

Plavix had already lost its patent protection in Europe. But its total turnover in 2011 reached 7 billion euros. This made so ephemeral, without doubt, the top-selling drug in the world, after the cholesterol-lowering Lipitor, sold by Pfizer, has lost its patent protection last November.

Clopidogrel, the active ingredient used for generic for Plavix and marketed by the French lab is fully produced Sisteron (04). However, the laboratory will manufacture other chemical molecules, which means that 500 jobs are not threatened by the loss of U.S. patent for Plavix, Sanofi sure.  

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Vincent Bolloré influence he soon the fate of Vivendi? Anyway, Jean-Rene Fourtou, Chairman of the Supervisory Board, opened the door. And will even wish his presence. "There is no reason that Bollore is not involved on the board of Vivendi, if he is interested," he said Thursday at the general meeting of shareholders of the group.

Intentions of the "Little Prince", which began rising in the capital of Vivendi, are at the heart of all searches. Bolloré officially 1.1% of the entertainment group, but it would have already picked up on the stock exchange securities for up to nearly 2%. After finalizing the sale of its channels Direct 8 Direct and Star in Vivendi, he will own approximately 4% and would then make its debut on the board. This rise is "friendly," said Vivendi every time. "I am delighted that a French shareholder, a family group, deemed an investor wishes to mount a share capital of Vivendi", was recently confirmed to Le Figaro, Jean-Bernard Levy, CEO of Vivendi.

And no doubt that Vincent Bolloré not stop there way. Eventually, he would seek the threshold of 5%. Does he repeat not at will, for years, his ambition to create a large media group? By becoming the largest shareholder of Vivendi and participating in strategic decisions of the group, it would be in a position to influence the destiny of the only French group, which is a world of entertainment. It could also help choose the future leaders of Vivendi.

Bring into the fold of Havas Vivendi

As the capital of Vivendi is very fragmented, with no shareholder, Bolloré could obtain decisive weight without having to own a large block of shares. As he did at Havas, which he chairs by not holding "only" 32.8%. One of the scenarios considered by the observers would, moreover, that Bolloré Havas brings into the fold of Vivendi, in exchange for participation, without spending a lot of cash.

The time was well chosen, while the price of Vivendi, has less than 13 euros, has lost more than a quarter of its value since the beginning of the year. "In the 2000s, all valuations were excessive, we experienced a kind of madness market. We live it the other way today, even though we have never had such good financial results, never reached as much cash, "said Jean-Rene Fourtou.

At Vivendi, more assets may be of interest Bolloré. Canal +, of course. But also SFR, including Jean-Rene Fourtou said she would remain "largely beneficial despite the arrival of Free Mobile". Telecommunications devices can be particularly useful in boss Autolib ', because there are many in the telecom management system and localization of the electric car self-service. Finally, Morocco Telecom, which holds several equity in Africa, can generate synergies with the Bolloré Group. Strong presence in logistics in Africa, Bolloré manages ports, railways … It may be wise to develop telecom. Add to this the fact that Jean-Rene Fourtou and Vincent Bolloré get along well. As for Jean-Bernard Levy, he is the former chief of staff … Gerard Longuet ex-brother-Vincent Bolloré. Such an alliance would have three advantages. It makes sense from a strategic perspective. It could have a positive effect on the course. Finally, it could offset the rise of sovereign wealth fund of Qatar, which owns 2% stake in Vivendi.

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Lactalis and its milk producers finally bury the hatchet. After several months of tensions, the global dairy products (Lactel, President, Galbani) reached an agreement Monday with representatives of its 14,500 producers, who collect five billion liters of milk. It took the intervention of the Ombudsman for agricultural trade relations as they agree to contracts that govern their trade relations now. Several calls to order the Minister of Agriculture have also been required to bend Lactalis. Among its competitors, including Bongrain or Danone, contracts have already been cordoned off.

The stakes are high. This is to prepare the end of milk quotas by 2015. Contracting business relationships between manufacturers and milk producers has been decided by the law of modernization of agriculture. Until then, these relationships worked on oral agreements, valid from generation to generation, and producers were paid on a monthly basis.

Reorganization of the sector

After several meetings, Lactalis and its producers have agreed on an "operating agreement". The Laval group is pleased to have offered "one of (the contract) most successful of the profession." It mainly offers "free transferability of the contract", the "no-monthly-payment imposed deliveries and settlement of supplies of milk in two monthly installments."

Especially, Lactalis has water in his wine, because the group now recognizes organizations (POs) as partners in the negotiations low fee payday loans. So far, the group wanted Laval to negotiate individually with producers, who feared an unfavorable balance of power.

A decree endorsing the creation of these organizations should be published shortly. OP local and regional associations of POs could coexist. Meanwhile, we must "work structuring" of these future producer organizations, Franck believes Guehennec, coordinator of the producer group Lactalis. "This is what one looks forward," he added.

Producers may elect by April 30 whether to integrate the OP. Still, many discussions always take place at industry level, such as on indicators for each company to fix the price of milk.

The agreement between Lactalis and its producers comes at a time of profound change in the sector, phase concentration, particularly in cooperatives. The number of farms (75,000 in total in France) is expected to decline over the coming years. Experts estimate that between 4,000 and 5,000 farms are disappearing each year as part of alliances, dispositions or retirements. These movements should also allow the emergence of true French champions.

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In computing, employment resists. According to forecasts by the Association for the employment of executives (APEC), the companies in this sector should recruit about 30,000 officers, as much as last year. Figures in line with those reported recently by Digital Syntec, professional organization IT services, software and technology consulting firm which focuses on "stability of recruitment in 2012" with the key more than 3500 new posts of which 80% of hiring managers and 35,000 in total. Despite a slowdown in growth, the sector remains a prime source of jobs for graduates: over half of the recruitments are for beginners or young engineers with less than five years experience.

Certainly, the lack of visibility is not conducive to economic euphoria. Currently, some larger customers put pressure on IT companies to lower prices and many projects are deferred. But at the same time, emerging markets draw activity and create jobs, especially for well-trained engineers. "These new deposits carriers include home automation, security or e-learning," says Philippe Tavernier, president of the Social Committee at Digital Syntec. Projects around mobility and modernization of information systems are also powerful engines of growth.

Impact of "cloud computing"

The "cloud" would be the most promising market. A new El Dorado for the employment of engineers? Régis Granarolo, president of Munci, a professional association of computer scientists, is a downside: "The cloud can probably create employment through the development of shared services, but it leads to losses due to outsourcing and the decrease in specific projects. Ultimately, the balance will be positive if the cloud goes heavily in SMEs and takes place in France and not through outsourced jobs. "

One thing is certain, the Internet continues to generate employment, particularly in start-up or well established web agencies. Ekino, the technology subsidiary of media group Fullsix, wants to recruit thirty engineers in 2012, mostly through job creation, to follow a strong growth poor credit personal loans. Developers 'front office', Java architects, engineers, computer scientists as PHP … that the company will most often seek out specialized schools. "Profiles so they asked are upping the ante on wages, laments Angel Michelozzi HRD Fullsix. Currently, existing courses do not produce enough of Internet developers. "

Consulting in SI, companies are also struggling to find the skills. For Neoxia, an SME with 50 people recruited fifteen engineers per year, these difficulties can be partly explained by a lack of appropriate training. "In general, curricula are five years late, sorry its CEO, Gilles Mergoil. If they can agree with the CAC 40, which are the last to adapt, they do not match the requirements of start-ups more advanced technologically. "

This "shortage", the employers also create themselves by finding all the same profiles of young engineers, rather, from the same schools and talent of communicating. "The skills are the foundation techniques, but the decision will be made on cross-curricular competencies, such as a sense of teamwork, listening skills, adapting to the culture of the company," said Francois Adoue, Director of the trades of the Internet. According to Bruno Fadda, associate director at Robert Half International, "the engineer of the Web, version 2012, must be strong technically but also have the marketing culture to meet clients' communications problems. A rare pattern. "

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In a mobile market completely disrupted by the arrival of Free Mobile, Bouygues Telecom said it had lost 159,000 customers, of which 134,000 went to Free Mobile. This represents 1.4% of its fleet of 11.3 million mobile customers. Last week, Orange announced that it had lost, for its part, 201,000 mobile customers in total, or 0.7% of its fleet.

Result, Bouygues Telecom expects a decline of 10% of its turnover in 2012 to 5.14 billion euros. The arrival of Free Mobile is not the only cause. Martin Bouygues, CEO of the group, also cited pell-mell "regulation, the end of the differential termination, terminal costs, Chatel law which is one of the most protective for the consumer."

 

Andy Adam, by creating the page "No refueling on March 1 in Germany!" Was a huge blip on the canvas, quickly picked up by media across the Rhine. With an average price of 1.70 euro per liter of super (against 1.55 in France), gasoline saw its flaming course in Europe since January 1. Claim of individuals joined those associations, as ADAC, powerful organization that unites over 17 million motorists across the Rhine.

Rising prices is certainly caused primarily by rising oil prices and problems in the Middle East, but the spokesman ADAC also shows the finger of responsibility oil majors: the rising price of a liter "is a matter for enterprises, which make huge profits with. The market is monopolized by five major companies, which are not competitive, "she told the daily Rheinische Post.  

A signal to policy

Calling on Facebook, even if it materializes Thursday, March 1, will not change the policies of the major oil companies: "This will have no effect," says a manager of Esso the region of Ulm in Bavaria, interviewed by Südwest Presse newspaper. "It does not annoy anyone. Right now there are even more and more people are filling up for fear that prices will rise again tomorrow. " The fuel will not be purchased on the first will be taken the next day, betting professionals.

This action and its resonance is still a strong signal to motorists to the German government, in a time when state coffers are full. The German tax authorities because it may alter several devices to reduce the cost of transportation. In addition to VAT and taxes that affect the fuel, the Ministry of Finance has the ability to play on the tax relief enjoyed by motorists. The ADAC claimed that assistance to motorists who use their cars to get to work from 30 to 40 cents per kilometer. The ministry declined for now to make a move. These are the neighboring countries who benefit: the Polish and Czech gas stations are under attack on the eve of the weekend.

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The scandal could not have been worse. While Air France is embarking on an extensive and highly unpopular savings plan, the unions of the company revealed Monday that their former boss Pierre-Henri Gourgeon was preparing to travel to destination in Mauritius with its Women in business class for 24 euros.

This trip was to take place almost free along with two relatives also enjoy preferential rates. These tickets are embargoed during the school holidays, Pierre-Henri Gourgeon had to obtain special approval of the new CEO of Air France, Alexander Juniac, to lift the embargo and travel to this destination.

"It's scary to work in this context, a sorry part of the company. Our company is mired in research and maintenance of personal advantages. How do you get the support of employees and pass a savings plan? ". Given the excitement that the information generated internally, the former boss has finally given up the tickets at unbeatable price and opted for traditional GP tickets entitlements in the company's employees and retirees.

The ex-boss will have to pay 745 euros to get to Mauritius in business class or about 1500 euros for a round trip ticket worth from 3000 to 6000 euro at full price. "When traveling in GP, ​​the former executives often take tickets in economy class, or 400 euros round trip to Mauritius, calculates an employee of the company paperless payday loans. Once on the plane, they do outperform if space is available at the front of the camera. "

"A trip to the Air France lounge"

Like many companies, employees of Air France benefit from preferential rates on their business activity. Like the employees of the car who pay their car cheaper, the Air France employees benefit from GP notes (Free partial), a valid right to life from 15 years of seniority. "I travel regularly to New York, welcomes a former executive of the company. It cost me about 200 euros in economy class, but in general I do upgrade and I manage to go on a trip to the Air France lounge. "

As a former senior executive, Pierre-Henri Gourgeon does not need to go through the system of GP tickets. Like other executives recently departed from the leadership, the former boss has negotiated a confidential volume of ticket prices almost free.

These benefits may soon be challenged. Juniac Alexander, the new leader of the company, has announced an overhaul of the benefits enjoyed by current and former executives of Air France. "Such benefits are not unique to Air France, says aviation expert. All major companies are considering a historic reform of the preferential fare tickets costing them too much. " And have less and less supported by employees who request efforts increasingly harsh.

 

Six applications studied, including two in the presence of the insured. As now regularly in each region, a commission composed of doctors and administration members met Thursday at Rennes, to review applications for "retirement hardship" from persons with a disability rating of 10 professional and 20% following an accident. The examination of each case lasted five to ten minutes.

First case: a nurse, since a car accident in 1993, has a disability rating of 12%. "The changes in schedules and staggered hours are hard to live, pleaded Mrs. C. before the six members of the commission. With the broken pelvis and legs that I had, car travel and care that I practice with dependents are painful. "The question is whether the sequelae to the accident could have been caused by an occupational disease caused through exposure for seventeen years to occupational hazards (heavy lifting, alternating schedules, handling chemicals, extreme temperatures …). "The answer is yes," has in this case ruled that the commission has approved the retirement at 60 years of Mrs. C.

Sleeping pills to sleep

"This is the absurdity of the law, recognizes a member. Two employees who had the same exposure to the same risks will not have the same rights as that one had an accident and the other not. "Besides, to be validated, the effects must be included a "list" of occupational diseases published by decree. A list that does not include … including amputation of fingers and led to "reject administratively" number of requests. "If the finger got caught, it's happening is in the list," quips a medical officer. "It would sew the finger," says Gerard Riviere, President FO Board of CNAV.

Another issue: a maintenance worker in a factory producing poultry meat that has had two accidents left him with "sequels in the left shoulder with residual pain" and a disability rating of 18%. "The hardest work is the 3 × 8, explained MD I started this morning at 4:00 am and afternoon next week. I take sleeping pills to sleep and am embarrassed when I have to intervene in height. "In his case, he also indicated to be exposed to chemical agents. "He has been confronted with all its risks, has recognized a member of the Committee in view of his career profile. He complains primarily of night work but it's exposure to all other risk factors that calls for him. "This opinion.

The Paris Bourse is trying to make a step forward on Tuesday, a day after falling more than 3%. The CAC 40 in advance from 1.6% to 2941.61 points in early trade.

The problems of sovereign debt, however, should still hang over the markets. The pressure rises in the euro zone since Moody's announced that the triple A French was threatened. Spain and Italy are always attacked in the bond markets. Finally, Germany is in the viewfinder of many observers who believe the country could experience a domino effect on the market.

But Europe is not the only one to raise the nervousness of the operators. The market should be affected by the fact that the "super committee" responsible for the debt of the United States do not reach an agreement between left and right, after three months of effort.The twelve members of the joint committee, composed of six Republicans and six Democrats were responsible for the deficit of 1200 billion and had until midnight Wednesday to share their findings. Failing agreement, the law provides for the automatic implementation, from 2013, these spending cuts divided equally between defense and social programs.

Fitch monitors the Americans

President Barack Obama assured that the United States were not at risk of default. He said he was determined to keep the pressure on elected officials and threatened to veto any attempt by Congress to mitigate the budget cuts that are now automatically take effect.

For now, the rating agencies Standard & Poor's and Moody's reported that U.S. credit rating would not be affected by the failure of these discussions.

The major index futures on Wall Street, announce an opening slightly lower on the NYSE. After four sessions of strong gains in a row investors should reap a share of their earnings per caution. Attention should be reinforced by several major deadline ahead.

Vote at high risk in Slovakia

Investors in the U.S. and Europe will continue to follow step by step développementsde the debt crisis in the eurozone. The latter is suspended by a vote very uncertain of the Slovak Parliament on Tuesday that could block the strengthening of the Financial Assistance Fund of the monetary union, the main instrument to hope to stop the contagion of the debt crisis, banks in particular.Investors also await the release later in the day of the minutes of the Fed and the announcement of Alcoa, the first tenor of the coast to announce its figures for the third quarter. The euro area, which has so far failed to stem the debt crisis, has the "political will" to overcome, reiterated on Tuesday German Chancellor Angela Merkel during a visit to Vietnam. Jean Claude Trichet, the outgoing president of the ECB, for his part said that "clear decisions" were necessary in view of the seriousness of the situation. He said the crisis has reached a "systemic dimension."

Berlin and Paris reassure markets

The willingness of the Franco-German recapitalize the banks and out of the spiral of debt crisis, like in Europe, supported investor sentiment for several days.Monday, U.S. President Barack Obama gave his full support "to the strategy of Nicolas Sarkozy and Angela Merkel." The latter, meeting in Berlin on Sunday pledged to respond "lasting and comprehensive peace" to the crisis in the euro area for the G20 summit in Cannes, 3 and 4 November. About the difficulties of the European banking sector, the two leaders said they were "determined to do whatever it takes to ensure the recapitalization of our banks." Again, the "details" will be specified later, they promised, while the EU summit scheduled for October 17 and 18 was postponed to October 23 to allow more time for officers to prepare a response "global" . Investors will pay particular attention to responses to the Greek question, the epicenter of the crisis.The leading European finance ministers, Jean-Claude Juncker, said yesterday that a discount of over 60% for creditors of Greece was possible.

First dance of Quarterly Results

In the U.S., the season of quarterly results of large companies to begin on Tuesday after the close of Wall Street. As usual, the aluminum giant Alcoa will kick-off for these publications. Follow in particular, PepsiCo Wednesday, Thursday, JPMorgan Chase and internet group Google and finally, Friday, Mattel. Analysts bet on an average increase of 13% earnings per share for the third quarter.

On the macroeconomic front U.S. investors await including the minutes of the last Fed meeting on Tuesday in 20 hours.

On the foreign exchange market, the euro is trying to go against the greenback.By late morning, the euro bought 1.3602 dollars against 1.3645 dollars late Monday. Oil is, him stable. The barrel of "light sweet crude" for November delivery gained 18 cents to 85.59 dollars. A barrel of Brent North Sea crude for November delivery gave a small 14 cents to 108.81 dollars.

Great success for the iPhone 4S

The side of values, Goldman Sachs should probably record a loss in the third quarter, which would be only the second quarterly loss in history of the giant Wall Street analysts expect Citigroup.

Apple announced its iPhone 4S has received one million pre-orders in the space of a day.By comparison, 600,000 pre-orders were recorded for the iPhone 4 in the first 24 hours.

Research in Motion announced Tuesday that its BlackBerry email and instant messaging were restored in Europe, the Middle East and Africa, nearly 20 hours after the crash reported in India and the region.

American Airlines announced a reduction in flights in coming months compared to the previous year, citing among other adverse economic conditions. American Airlines said its capacity during "the late fall and winter" would be reduced by 3% over the previous year.

The title of the group that Alcoa is required to publish its quarterly results after the market will be particularly surrounded.